Chemotherapy-associated recurrent pneumothoraces in lymphangioleiomyomatosis.

Department of Medicine and Therapeutics, University College Dublin, St Vincent's University Hospital, Elm Park, Dublin 4, Ireland. emermariekelly@hotmail.com.

Lymphangioleiomyomatosis is a rare cause of pneumothorax in women. We present the case of a 48-year-old woman with lymphangioleiomyomatosis, who had never had a pneumothorax prior to commencing chemotherapy for breast cancer. During chemotherapy she developed 3 pneumothoraces and 2 episodes of pneumomediastinum. We suggest that the pneumothoraces were caused by the chemotherapy. To our knowledge, this is the first reported case of chemotherapy triggering pneumothoraces in a woman with lymphangioleiomyomatosis.

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